Mesothelioma Blog

Asbestos pollution
The world used about 95% for chrysotile asbestos, the fiber can be split into thin element fiber, industrial consumption of each 1 tons of asbestos has about 10 grams of asbestos fiber release to the environment. 1 kg of asbestos containing about 100 of Wan Genyuan fibers. Element fiber diameter typically 0.5 microns, length of 5 microns or less, in the air and water can be suspended for several weeks, several months, continue to cause pollution. Studies have shown, and asbestos related diseases in a variety of industrial occupation is ubiquitous. Such as asbestos mining, processing and use of asbestos and asbestos containing materials in all walks of life ( buildings, ships and auto repair, metallurgy, textile, mechanical and electrical engineering, chemistry, agriculture etc.).
The United States Environmental Protection Agency has some restrictions such as the use of asbestos products, issued in 1972, the ban on asbestos fiber spraying refractory coating regulations. Read the rest of this entry »

Localized pleural mesothelioma cells are immature mesenchymal cells, which exist in the pleural mesothelial cell layer of loose connective tissue, and not due to pleural mesothelial cells. So I think the best is the noun” pleural localized benign fibrous tumor ( malignant )”. In addition, the indirect evidence is observed in the patients without a history of asbestos exposure, and diffuse malignant mesothelioma is significantly different, the latter more than 60% of patients have a history of asbestos exposure. Are benign, potentially malignant, 30% with malignant pleural effusion, and easy to relapse, much as epithelial or hybrid. Clinical report of.
The 1 type are localized mesothelioma is divided into the following 3 types: epithelial type, fiber type and mixed type.
2 most benign localized fibrous tumor of the pleura ( BLFT ) located in the visceral pleura or leaf between pleural nodules, slow growth. Into the pleural cavity pedunculated growth, there are sessile and attached to the pleural surface. To the pulmonary parenchyma growth are not common, but only a few of the BLFT lung and pleural, mostly septal interstitial cells, or lung tissue origin. The tumor may be located within the lobed leaves, benign BLFT can also be found in various parts of the parietal pleura, however the site of the tumor and the leaf lobes or whom intrapulmonary often suggested a malignant.

Pleural mesothelioma ( Department of respiratory medicine ) for primary tumors of the pleura, is derived from the visceral layer, wall, mediastinum or diaphragmatic part four pleural tumor. The incidence is higher than that of domestic abroad, each is 0.07 ~ 0.11% and 0.04%. Mortality in the world for all 1% tumors of the following. In recent years there has been a marked rise trend. Over 50 years of age to see more, and the ratio of male to female was 2: 1. And related to asbestos exposure. At present, the malignant type is still lack of effective treatment.
According to statistics, malignant pleural mesothelioma patients more males than females ( 2: 1). Most of the patients in the 40 ~ 70 years between foreign patients, mean age of 60 years, our country only 45.2 years old. The first symptoms were chest pain, cough and shortness of breath are most common, and about 10.2% of patients with fever and sweating, 3.2% patients with symptoms of joint pain as chief complaint. Due to diaphragmatic involvement, chest pain can be conducted first abdominal and ipsilateral shoulder. About 50% to 60% of patients with massive pleural effusion with serious shortness of breath, which accounted for 3 / 4 bloody pleural effusion. Without massive pleural effusion of patients with chest pain is severe. Weight loss common. Some patients appear periodic hypoglycemia and hypertrophic pulmonary osteoarthropathy, but these indications in benign mesothelioma see more.
Epithelial type and mixed type of pleural mesothelioma is often accompanied by massive hydrothorax, and fiber type usually have little or no effusion. Epithelial type patients seem to be more midshaft clavicle or axillary lymph node and extends to the pericardium, contralateral pleural and peritoneal; fiber type to have distant metastasis and bone metastasis. Radiology indications: common chest X-ray revealed pleural effusion, pleural 50% Chang Zhan side. Ipsilateral pulmonary tumor tissue parcel, mediastinal shift to side of the tumor, ipsilateral pleural smaller condition advanced chest without mediastinal widening, pericardial effusion that the heart expands, the visible soft tissue image and rib destruction. Read the rest of this entry »

Malignant mesothelioma of the pleura histologically composed of fibroblasts and epithelial cell components. According to the morphology of malignant mesothelioma has 3 main subtypes: epithelial type, sarcoma and bipolar ( or hybrid ), respectively 60%, 20% and 20%. Mesothelioma of poor prognosis, 3 subtypes of median survival time were 18 months, 8 months and 11 months. Other more rare special type also includes signet-ring cell type, small cell type, myxoid, myofibroblasts, lymphoid tissue, cell type, desmoplastic etc..
Malignant mesothelioma can be roughly divided into limited and diffuse type, the latter incidence was significantly higher than that of the former. Localized pleural mesothelioma diagnosis more in the past, but the type of diagnosis for solitary fibrous tumor, because both immunohistochemistry and morphology are not to endothelial cell differentiation characteristics, its original cell marker CD34 positive. The mesothelioma are of different types, and asbestos exposure. Pleural mesothelioma as early manifestations of parietal pleural nodules, then along the pleural surface growth, parietal and visceral pleural adhesions, final tumor surrounding lung parenchyma.

1 benign pleural mesothelioma in limitations of growth, it is also known as benign localized pleural mesothelioma. ( 1) the tumor often enveloped circular lump, basal part can be smaller, pedunculated and pleural connected, or sessile and pleura. Some tumors can be lobulated, solid. Most tumor body is smaller, the average diameter of 1 ~ 3cm, also have a diameter of more than 12cm. ( 2) microscopic tumor tissue is mostly composed of spindle-shaped fibroblasts tumor cells, arranged in a manner like fibroma. Part of the tumor in the fibroblast-like cells in epithelial tumor cells formed tubular or papillary, entity structure, called bidirectional mesothelioma. This tumor growth is slow, easy operation resection. After excision with minimal recurrence, a favorable clinical prognosis.
2 malignant pleural mesothelioma: a highly malignant tumor, the tumor along the pleural surface diffu Read the rest of this entry »

South Korean media reported recently, including the German NUK baby powder brands, including 12 kinds of products found to contain a powder of a carcinogen asbestos is disabled. The news caused a panic in the country, leading to this powder in the country round the shelves.

    Powder is not necessary to use asbestos, manufacturers can not intend to add asbestos. Asbestos is how it went to baby powder? This is because the powder contains other minerals talc, and talc and asbestos-containing ingredients are often serpentine mixed together, so sometimes containing talc was asbestos products. In 2000 the United States had similar incidents. There is a laboratory tested eight brands of children’s crayons and found three brands are the 40 crayons contain asbestos, the reason is that crayons contain talc. Later, these crayon manufacturers have agreed not to use talc in their products.

    Asbestos is a fibrous mineral collectively six kinds, white, blue, green, gray and other types of colors, the most common is “chrysotile.” Asbestos was called such a name, because some of its long and soft fibers, like cotton can be used to weaving. And cotton, but the difference is, asbestos because it is “stone”, so fire. Humans long ago asbestos mining, manufacturing is not afraid to use it to set fire to the clothes, they are dirty, with a burning fire, it has white as before, so the use of fire to the ancient Chinese called the wash cloth – “Fire Low cloth.” . Roman restaurants like to use to do asbestos cloth, another wave of customers on the go, fling the wallpaper to the fire, burned grease, food residue, and can shop on the table to meet the next wave of customers. Read the rest of this entry »

The world’s first drug for the treatment of pleural mesothelioma, “Alimta” officially in the domestic market. This is the only for the treatment of advanced malignant pleural mesothelioma drugs.

         Pleural mesothelioma is a rare lung breast cancer, its incidence and asbestos exposure related, because a long incubation period, most patients had been diagnosed at a late stage, generally can not be surgery or radiotherapy. According to statistics, every year 10,000 to 15,000 people are diagnosed with malignant pleural mesothelioma. With the asbestos industry, this number is increasing every year.

         Studies have shown, “Alimta” survival of cancer cells can also block the three enzymes are very important to prolong the survival time of patients, significant improvement in patient quality of life; Meanwhile, folic acid and vitamins to control side effects, enhance the patient’s tolerance.

         In February 2004, by the U.S. research and development of Lilly’s new drug, “Alimta”, the U.S. Food and Drug Administration (FDA) approval, a late first-line treatment of malignant pleural mesothelioma drugs. Not long ago, the drug was given a Chinese State Food and Drug Administration (SFDA) issued by the production of the text. Currently, the drug has been listed in more than 60 countries worldwide sales in 2004 reached $ 140 million.

“Malignant pleural mesothelioma with high disability and mortality, and can easily be misdiagnosed, difficult surgery, which is generally considered incurable from the current information, the exposure to asbestos improperly prone to cause malignant pleural mesothelioma tumor, and according to the law of its incidence is estimated that China will usher in the peak incidence of malignant pleural mesothelioma. ”

Recently, Shanghai Clinical Center of lung cancer expert Professor Liao Meilin, chief called, “Although malignant pleural mesothelioma tumors accounted for only 5% of the entire chest, compared with common tumor incidence is much lower, but the incidence of the world is rising from our point of view, the annual incidence rate of 0.04%, annual number of new-onset patients in more than 50 million people. “Professor Liu said,” As the disease latency period of 20 to 30 years, and cause of the disease is not fully clear, at present only known asbestos exposure, viral infection, so prevention is a difficult task, can not be ignored! ”

Patients with chest pain difficulty breathing extremely painful Read the rest of this entry »

First, what is pleural mesothelioma []

    Pleural mesothelioma is pleural primary tumor, there are localized (mostly benign) and diffuse (all malignant) points. Which diffuse malignant mesothelioma of the chest tumor one of the worst prognosis. Most patients in the 40-70 years old, more men than women. The first symptom of chest pain, cough and shortness of breath is the most common. Have fever, sweating or joint pain mainly v. symptoms. About half of the patients had a large pleural effusion with severe shortness of breath. No large pleural effusion are often more severe chest pain, weight loss common. Ordinary X-ray found that pleural effusion, and lung tumor tissue was wrapped, etc., in advanced cases may have pericardial effusion caused by heart shadow expansion and soft tissue and rib destruction. For patients with suspected malignant pleural mesothelioma, CT examination is most useful. Pleural fluid cytology are helpful in the diagnosis. Routine laboratory tests, some patients may have thrombocytosis, serum carcinoembryonic antigen (CEA) level rise.

Second, how the [cause of pleural mesothelioma, pleural mesothelioma and the relationship between acidic]

    Pleural mesothelioma is the most representative endogenous diseases, like normal cells, Read the rest of this entry »

Most malignant mesothelioma is due to long-term work in asbestos environment, incoming live in contact with asbestos or asbestos caused the family environment. In rare cases, even exposure to asbestos can cause mesothelioma, a month. National Cancer Institute definition of mesothelioma: Mesothelioma is a rare find in the mesothelial cells of malignant cancer. Most patients suffering from mesothelioma due to asbestos floating work environment, which caused the inhalation of asbestos particles. Frequent lung mesothelioma or abdominal membrane. Although this disease usually takes several decades in the form of asbestos exposure, mesothelioma, but once there, it will spread and deteriorate very quickly. Because the symptoms of mesothelioma and other diseases is very much the same light, with the onset of the disease for a long time interval, mesothelioma patients generally have to wait until after the onset of the disease in order to feel the symptoms. . What is mesothelioma? Pleural mesothelioma is pleural primary tumor, there are localized (mostly benign) and diffuse (all malignant) points. Which diffuse malignant mesothelioma of the chest tumor one of the worst prognosis. The first symptom of chest pain, cough and shortness of breath is the most common. Have fever, sweating or joint pain mainly v. symptoms. About half of the patients had a large pleural effusion with severe shortness of breath. No large pleural effusion are often more severe chest pain, common weight loss. Ordinary X-ray found that pleural effusion, and lung tumor tissue was wrapped, etc., in advanced cases may have pericardial effusion caused by heart shadow expansion and soft tissue and rib destruction. For patients with suspected malignant pleural mesothelioma, CT examination is most useful. Pleural fluid cytology are helpful in the diagnosis. Routine Read the rest of this entry »